The Subcommissural Organ: An Ependymal Brain Gland

The subcommissural organ is a secretory ependymo-glial structure of the brain. It secretes glycoproteins into the crebrospinal fluid. The chemical nature of this material is only partly known, and the functional role of theentire circumventricular complex has remained enigmatic. New experimental models include transplantation, immunological blockade,and experimental and clinical hydrocephalus. This first book in the field containing provocative ideas will most likely stimulate further investigations into molecular and systemic aspects of the problem.